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DUAL ROLES OF URIC ACID IN AODS Contrary to the traditional understanding as a metabolically inert and waste compound without any physiological significance, UA is a natural antioxidant contributing to approximately 60% of the free radical scavenging activity in human blood (Ames et al., 1981)

Participants in combination studies showed meaningful reductions in HbA1c, often exceeding 1.5 percentage points from baseline

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pH profiles indicative of rate-limiting nucleophilic displacement in thioltransferase catalysis

These assays confirmed the plant's strong antioxidant activity, which was attributed to the high concentrations of phenolic and flavonoid compounds present in the extracts